要約

• Group of protozoan diseases that infect humans and mammals, causing 2 major clinical syndromes: skin ulcers and systemic illness affecting the reticuloendothelial system (spleen, liver, and bone marrow). The main route of transmission is via the bite of the phlebotomine sand fly.
• Includes a range of clinical presentations: cutaneous or visceral leishmaniasis.
• Possible treatments depend on clinical presentations, parasite species and strain, and the part of the world in which infection occurs.
• Treatment is less effective and more toxic in immunocompromised than in immunocompetent people.