Summary

  • Sudden onset of respiratory or cardiovascular compromise, usually with a history of allergen exposure presumably in sensitised individuals.
  • Skin rash, wheezing and inspiratory stridor, hypotension, anxiety, nausea, and vomiting are the cardinal signs and symptoms.
  • The diagnosis is clinical. Allergy testing is helpful only for secondary prophylaxis.
  • Securing the airway and initiating prompt treatment with epinephrine (adrenaline) may save lives.
  • Comorbidities (e.g., CAD and COPD) may pose a treatment challenge and warrant expert consultation

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