- Sudden onset of respiratory or cardiovascular compromise, usually with a history of allergen exposure presumably in sensitised individuals.
- Skin rash, wheezing and inspiratory stridor, hypotension, anxiety, nausea, and vomiting are the cardinal signs and symptoms.
- The diagnosis is clinical. Allergy testing is helpful only for secondary prophylaxis.
- Securing the airway and initiating prompt treatment with epinephrine (adrenaline) may save lives.
- Comorbidities (e.g., CAD and COPD) may pose a treatment challenge and warrant expert consultation