Encephalitis

Summary

  • Pathological state of brain parenchymal dysfunction leading to an altered state of consciousness or focal neurological signs.
  • Serious, complex, and potentially fatal disorder with non-infectious and infectious causes.
  • Presents with acute onset of a febrile illness and altered mental status; typical features include headache, seizures, and focal neurological signs.
  • Investigations should include blood cultures, neuroimaging (preferably MRI), and CSF analysis.
  • Aciclovir should be given in all cases of suspected viral encephalitis.
  • Complications include seizures, hydrocephalus, and neurological sequelae (e.g., behavioural disturbances, neuropsychiatric problems, and motor problems).
Last updated: Jul 27, 2012
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