- Calcium pyrophosphate arthritis is caused by deposition of calcium pyrophosphate (CPP) crystals.
- It can be difficult to diagnose as CPP crystals in synovial fluids can be small, sparse, and difficult to find.
- In patients <60 years of age, underlying metabolic conditions associated with calcium pyrophosphate deposition (CPPD), such as hyperparathyroidism or haemochromatosis, should be investigated.
- There is no definitive treatment for CPP arthritis but intra-articular corticosteroids can be effective for both acute and chronic forms.
Last updated: Aug 13, 2012