- An inflammatory arthritis predominantly affecting the sacroiliac joints and axial spine.
- Classified as a seronegative spondyloarthropathy. The seronegative spondyloarthropathies (including psoriatic arthritis, enteropathic arthritis, and reactive arthritis) are a heterogenous group of conditions with overlapping clinical manifestations and association with the gene HLA-B27.
- Inflammatory back pain is the hallmark clinical feature. This is defined as back pain that is of insidious onset, is worse in the morning, and improves with exercise.
- A positive response to non-steroidal anti-inflammatory drugs (NSAIDs) is characteristic of most patients.
- Physiotherapy and NSAIDs are the cornerstone of treatment. In refractory patients, tumour necrosis factor (TNF)-alpha inhibitors play a key role.
Other related conditions
- Overview of musculoskeletal pain
- Assessment of back pain
- Assessment of neck pain
- Assessment of palpitations
- Degenerative cervical spine disease
- Discogenic low back pain
- Musculoskeletal lower back pain
- Overview of dysrhythmias (cardiac)
- Crohn's disease
- Ulcerative colitis
- Reactive arthritis
- Juvenile idiopathic arthritis
- Aortic regurgitation
Last updated: Nov 14, 2012