- Autosomal inheritance with variable penetrance and phenotypic expression.
- Usually presents with mucocutaneous bleeding.
- Menorrhagia and postpartum haemorrhage common in affected females.
- Joint bleeding rare and seen only in patients with more severe disease.
- Most patients have type 1 von Willebrand disease; more severe symptoms are seen in types 2 and 3.
- Clinical bleeding scores may be helpful in identifying patients with disease.
Last updated: Oct 04, 2012