Cocaine overdose

Summary

  • Occurs within minutes to hours of excessive cocaine use.
  • Some patients may die suddenly before treatment is given.
  • Presentation includes tachycardia, hypertension, hyperthermia, diaphoresis, mydriasis, and agitation.
  • Urine cocaine screen confirms recent cocaine use, but treatment should not be delayed pending results of the test.
  • Treatment may involve supportive care and benzodiazepines; hyperthermia requires rapid cooling to prevent death.
  • Complications such as dysrhythmias, acute coronary syndrome, and intracranial haemorrhage can occur.
Last updated: Apr 03, 2013
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