- Typically a single large thyroid nodule accompanied by clinical and biochemical hyperthyroidism.
- Diagnosis confirmed by thyroid scan demonstrating a hot area and suppression of extranodular thyroid tissue.
- Hyperthyroidism caused by toxic adenomas generally does not remit.
- Definitive treatment, such as radioactive iodine therapy, is usually required.
- Complications of untreated toxic adenomas may include sequelae of hyperthyroidism such as cardiac dysfunction or bone loss, or tracheal compression by large nodules.
Last updated: Apr 10, 2013