- Sarcoma is a group of rare solid tumours of connective tissue. More than 50 different histological subtypes are known.
- Most commonly, it presents as a soft-tissue swelling, which may or may not be painful. Differential diagnoses that should be considered are lymphoma, metastatic carcinoma, and benign lesions such as lipoma and neuroma.
- Some sarcomas are associated with specific gene mutations, in particular chromosomal translocations.
- Diagnosis is made by biopsy, which should have a sufficient amount of tissue for accurate pathological diagnosis.
- Pathology should be reviewed by an expert pathologist who has experience in sarcoma histology. Diagnostic laboratory methods may include immunohistochemistry, cytogenetics, and molecular genetic testing.
- Treatment is based on stage and histological subtype, with only some subtypes being chemotherapy-sensitive.
Other related conditions
- Kaposi's sarcoma
- Uterine fibroids
- Acoustic neuroma
- Infectious mononucleosis
- Assessment of upper gastrointestinal bleeding
- Assessment of lower gastrointestinal bleeding
- Assessment of acute abdomen
- Type 1 neurofibromatosis
- Infertility in women
- Male factor infertility
- Peptic ulcer disease
วันที่ปรับปรุง: มี.ค. 05, 2012