Summary

• Cancer that develops in any portion of the stomach and may spread to other organs.
• Presents with weight loss and abdominal pain, although patients with proximal or gastro-oesophageal junction tumours may present with dysphagia.
• Upper GI endoscopy with biopsy demonstrating carcinoma is required to confirm the diagnosis. Staging based on imaging is required.
• Early-stage disease is treated with surgery alone.
• Advanced disease should undergo surgery followed by postoperative chemoradiation, or chemotherapy before and after surgery.
• Metastatic disease is treated with chemotherapy or chemoradiation and supportive care measures.
• Common complications are gastric bleeding and obstruction.