- Chronic inflammatory and auto-immune disorder characterised by diminished lacrimal and salivary gland secretion (sicca complex).
- May present with fatigue and dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia).
- Diagnosed by positive ANAs, anti-60 kD (SS-A) Ro and anti-La auto-antibodies, decreased saliva and tear production, lymphocytic infiltration in labial salivary gland biopsy.
- Treatment mainly symptomatic.
Last updated: Dec 28, 2012