History & exam
Key factors
- presence of risk factors
- cough
- fever
- anorexia
- weight loss
- malaise
Other diagnostic factors
- night sweats
- pleuritic chest pain
- haemoptysis
- psychological symptoms
- abnormal chest auscultation
- asymptomatic
- dyspnoea
- clubbing
- erythema nodosum
History & exam details
Diagnostic tests
1st tests to order
- CXR
- sputum smear
- sputum culture
- FBC
- nucleic acid amplification tests (NAAT)
Tests to consider
- gastric aspirate
- bronchoscopy and bronchoalveolar lavage (BAL)
- tuberculin skin testing (TST)
- interferon-gamma release assays (IGRAs)
- empirical treatment
- susceptibility testing
- genotyping
- HIV test
- CT of chest
- Xpert MTB/RIF
Diagnostic tests details
Treatment details
Presumptive
latent TB: non-pregnant HIV-negative
- anti-tuberculosis treatment for latent infection
latent TB: non-pregnant HIV-positive
- anti-tuberculosis treatment for latent infection
latent TB: pregnant
- anti-tuberculosis treatment for latent infection
Acute
active TB HIV-negative non-pregnant: no hepatic dysfunction
-
multidrug resistance not suspected
- initial phase therapy
- continuation phase therapy
-
with multidrug resistance
- speciality consultation
active TB HIV-positive non-pregnant: no hepatic dysfunction
-
multidrug resistance not suspected
- initial phase therapy
- continuation phase therapy
-
multidrug resistance
- speciality consultation
active TB pregnant
- speciality consultation
active TB non-pregnant: pre-existing or drug-induced hepatic dysfunction
- speciality consultation
Ongoing
recurrent TB
- speciality consultation
Treatment details
Last updated: Feb 04, 2013
