Bronchiolitis obliterans organising pneumonia

Zusammenfassung

  • An inflammatory disorder involving both the peripheral bronchioles and alveoli simultaneously. It has distinctive radiographic findings, histological features, and response to corticosteroids (unlike usual interstitial pneumonia).
  • Most common type is idiopathic BOOP; other types include focal nodular, post-infection, drug-related, rheumatological, immunological, organ transplantation, radiotherapy, environmental, and miscellaneous BOOP.
  • Accounts for 20% to 30% of all cases of chronic infiltrative lung diseases. It occurs equally among men and women, and is not related to smoking.
  • High-resolution chest CT scan shows bilateral patchy triangular ground glass opacities with air bronchograms usually located peripherally.
  • Lung biopsy may be required to establish the definitive diagnosis in patients with unusual findings or severe disease.
  • Idiopathic BOOP is treated with corticosteroids.
  • Cases with an underlying cause (e.g., drug-related BOOP) should have the causative factor removed; corticosteroid therapy is indicated in some cases.
Letzte Aktualisierung am: Mai 21, 2013
Top

Use of this content is subject to our disclaimer