- The most common type is squamous cell carcinoma.
- Associated with HPV infection and common in men who have sex with men and in immunosuppressed patients, especially those who are HIV-positive.
- Presenting symptoms are typically bleeding and anal pain.
- The cure rate is high (75% to 90%).
- Most patients are cured without a colostomy.
- Standard treatment for anal cancer is fluorouracil/mitomycin plus radiotherapy.
- More intensive chemotherapy and radiation has not improved results.
Last updated: Nov 19, 2012