- In humans, Yersinia pestis causes plague, and Yersinia enterocolitica and Yersinia pseudotuberculosis cause yersiniosis.
- Plague affects many parts of the world, particularly Asia and Africa.
- The relative ease of culture and high fatality rates make Y pestis a potential biological weapon.
- Diagnosis of plague may be suggested by characteristic clinical findings (e.g., fever, lymphadenitis) together with a history of potential exposure in an endemic area. Yersiniosis presents generally as a self-limiting gastroenteritis, but invasive infection may occur. Microbiological studies are used to confirm a suspected diagnosis.
- Treatment of plague includes parenteral antibiotics. In a mass casualty setting (bioterrorist attack), oral therapy may be indicated. Early treatment is essential. A delay of >24 hours from the onset of systemic symptoms is associated with a high mortality.
- Post-exposure antibiotic prophylaxis is indicated in people who have been in close contact (within 2 m) with people with plague.
- Yersiniosis requires supportive care. Treatment with intravenous antibiotics is appropriate in patients with invasive infection.
Other related conditions
- Viral gastroenteritis
- Viral gastroenteritis in children
- Overview of pneumonia
- Reactive arthritis
- Shigella infection
- Clostridium difficile-associated disease
- Foodborne E coli infection
- Non-cholera Vibrio infections
- Acute appendicitis
- Mycobacterium avium-intracellulare
- Assessment of acute diarrhoea
last updated:=최종 업데이트: 4월 29, 2013