Alcoholic liver disease

Zusammenfassung

  • Caused by chronic heavy alcohol ingestion. About 40 to 80 g/day in men and 20 to 40 g/day in women for 10 to 12 years is sufficient to cause liver damage in the absence of other liver diseases.
  • Clinical presentations are highly variable. There is no specific laboratory test to identify alcohol as a cause of liver damage. Liver biopsy, in the context of a history of alcohol abuse, is diagnostic but is not absolutely indicated in all patients.
  • Alcohol abstinence is the first line of treatment, with periodic liver enzyme tests to monitor ongoing liver damage. Abstinence is also the key to prevention of alcoholic liver diseases.
  • Complications such as oesophageal or gastric variceal bleeding, ascites, coagulopathy, hepatic encephalopathy, and liver cancer are associated with the disease.
Letzte Aktualisierung am: Nov 27, 2012
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