- A defect in the interventricular septum that allows shunting of blood between the left and right ventricles.
- Usually congenital, but rarely acquired after myocardial infarction or trauma.
- May be associated with other congenital defects such as tetralogy of Fallot.
- Significant left-to-right shunting results in pulmonary hypertension, which, if left untreated, can progress to shunt reversal with cyanosis and the Eisenmenger's syndrome.
- Small shunts may close spontaneously in childhood and can be managed by observation.
- Large shunts require surgical closure.
Other related conditions
- Overview of congenital heart disease
- Tetralogy of Fallot
- Down's syndrome
- Infective endocarditis
- ST-elevation myocardial infarction
- Non-ST-elevation myocardial infarction
- Atrial septal defects
- Patent ductus arteriosus
- Mitral regurgitation
- Tricuspid regurgitation
- Pulmonary stenosis
- Aortic regurgitation
- Atrioventricular block
Last updated: Nov 19, 2012