- Migraine is a chronic, genetically determined, episodic, neurological disorder that usually presents in early-to-mid life.
- Patients complain of intermittent headache and associated symptoms, such as visual disturbance, nausea, vomiting, and sensitivity to light or noise (photophobia and phonophobia).
- The diagnosis is based on history and physical examination. No laboratory or imaging tests are essential for diagnosis.
- Treatment approaches involve identification and avoidance of trigger factors, and the use of medication to treat the acute attack or prevent future attacks.
- There are no clinical trials that identify one migraine therapy (acute therapy or prophylaxis therapy) as superior over others. Triptans in general are preferred over non-specific treatments. However, there are no trials directly comparing triptans.
- Complications include status migrainosus, migrainous infarction, chronic migraine, persistent aura without infarction and seizures, analgesic gastropathy, transformation of episodic to chronic migraine, and medication-overuse headache.
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Last updated: Dec 03, 2012